1.
Clin Chem Lab Med
; 58(11): e251-e253, 2020 10 25.
Article
in English
| MEDLINE | ID: covidwho-1574887
Subject(s)
Antibodies, Viral/blood , Betacoronavirus/immunology , Coronavirus Infections/diagnosis , Pneumonia, Viral/diagnosis , Adult , Aged , COVID-19 , COVID-19 Testing , Clinical Laboratory Techniques , Electrochemical Techniques/methods , Female , Humans , Immunoassay/methods , Luminescent Measurements/methods , Male , Middle Aged , Pandemics , SARS-CoV-2
2.
Clin Chem Lab Med
; 58(7): 1156-1159, 2020 06 25.
Article
in English
| MEDLINE | ID: covidwho-976023
Subject(s)
Betacoronavirus/immunology , Coronavirus Infections/diagnosis , Coronavirus Infections/immunology , Pneumonia, Viral/diagnosis , Pneumonia, Viral/immunology , Automation, Laboratory/methods , Betacoronavirus/pathogenicity , COVID-19 , Humans , Immunoenzyme Techniques/methods , Immunoglobulin G/immunology , Immunoglobulin M/immunology , Luminescence , Pandemics , SARS-CoV-2
3.
Eur J Clin Microbiol Infect Dis
; 40(4): 897-900, 2021 Apr.
Article
in English
| MEDLINE | ID: covidwho-880322
ABSTRACT
Results of three rapid immunochromatographic tests (ICTs) were compared with those obtained with two automated immunoassays for evaluation of their usefulness. One hundred fifty-nine patients and 67 healthy volunteers were included. Different assays demonstrate 41-45% of diagnostic sensitivities and 91-98% of specificities, with substantial agreement (89.3-91.2%), but a high percentage of weak positive results (13-22%) was observed with ICTs. ICTs performances were comparable to those of automated immunoassays. ICTs could have a role as screening approach due to their easy usability. Subjective interpretation, significant rate of uncertain results, uncertainty on viral antigens source are undoubtedly drawbacks.